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Kristoffer Valerie Selected Research

Polyribonucleotide Nucleotidyltransferase (Polynucleotide Phosphorylase)

5/2008Progression elevated gene-3 promoter (PEG-Prom) confers cancer cell selectivity to human polynucleotide phosphorylase (hPNPase(old-35))-mediated growth suppression.
7/2003Down-regulation of Myc as a potential target for growth arrest induced by human polynucleotide phosphorylase (hPNPaseold-35) in human melanoma cells.

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Kristoffer Valerie Research Topics

Disease

35Neoplasms (Cancer)
12/2020 - 02/2003
15Glioma (Gliomas)
12/2020 - 03/2002
10Melanoma (Melanoma, Malignant)
10/2019 - 07/2002
8Ataxia Telangiectasia (Louis Bar Syndrome)
01/2018 - 09/2003
8Breast Neoplasms (Breast Cancer)
05/2015 - 07/2002
8Infections
03/2015 - 07/2002
8Carcinoma (Carcinomatosis)
12/2012 - 06/2002
6Brain Neoplasms (Brain Tumor)
12/2020 - 02/2003
4Glioblastoma (Glioblastoma Multiforme)
01/2018 - 03/2012
3Neoplasm Metastasis (Metastasis)
10/2019 - 12/2005
3Spinocerebellar Ataxias (Spinocerebellar Ataxia)
08/2009 - 01/2005
3Pancreatic Neoplasms (Pancreatic Cancer)
05/2008 - 10/2005
2Lung Neoplasms (Lung Cancer)
01/2018 - 01/2014
1Craniopharyngioma (Craniopharyngiomas)
01/2020
1Bites and Stings (Sting)
01/2019
1Communicable Diseases (Infectious Diseases)
01/2019
1Nijmegen Breakage Syndrome
01/2017
1Hypoxia (Hypoxemia)
01/2013
1Genomic Instability
09/2012
1Wounds and Injuries (Trauma)
09/2012
1Ovarian Neoplasms (Ovarian Cancer)
02/2012
1Hypersensitivity (Allergy)
08/2009
1Chromosome Breakage
08/2009
1Neurodegenerative Diseases (Neurodegenerative Disease)
05/2009
1Heart Failure
01/2008
1Prostatic Neoplasms (Prostate Cancer)
01/2007

Drug/Important Bio-Agent (IBA)

13Proteins (Proteins, Gene)FDA Link
10/2017 - 07/2002
8ErbB Receptors (EGF Receptor)IBA
12/2020 - 07/2002
8Phosphotransferases (Kinase)IBA
01/2014 - 01/2006
6DNA (Deoxyribonucleic Acid)IBA
01/2018 - 01/2005
6Messenger RNA (mRNA)IBA
02/2006 - 07/2002
5epidermal growth factor receptor VIIIIBA
12/2020 - 08/2003
51,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
01/2017 - 09/2003
4CytokinesIBA
01/2019 - 05/2004
3Therapeutic UsesIBA
10/2020 - 01/2013
3SynteninsIBA
10/2019 - 12/2005
3Reactive Oxygen Species (Oxygen Radicals)IBA
10/2013 - 03/2007
32- (2,6- dimethylmorpholin- 4- yl)- N- (5- (6- morpholin- 4- yl- 4- oxo- 4H- pyran- 2- yl)- 9H- thioxanthen- 2- yl)acetamideIBA
06/2013 - 10/2009
3InterleukinsIBA
08/2006 - 05/2004
3Transcription Factors (Transcription Factor)IBA
02/2006 - 07/2002
2Ataxia Telangiectasia Mutated ProteinsIBA
01/2018 - 09/2003
2CamptothecinIBA
01/2015 - 12/2012
22- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
01/2015 - 11/2012
2LuciferasesIBA
01/2013 - 01/2013
2Polyribonucleotide Nucleotidyltransferase (Polynucleotide Phosphorylase)IBA
05/2008 - 07/2003
2Interleukin-10 (Interleukin 10)IBA
08/2006 - 05/2004
2p38 Mitogen-Activated Protein KinasesIBA
08/2006 - 07/2002
2EnzymesIBA
08/2005 - 12/2002
1Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
12/2020
1Pharmaceutical PreparationsIBA
10/2020
1Adenosine Monophosphate (AMP)IBA
01/2019
1bis(3',5')-cyclic diguanylic acidIBA
01/2019
1cyclic diadenosine phosphateIBA
01/2019
1cyclic guanosine monophosphate-adenosine monophosphateIBA
01/2019
1Guanosine Monophosphate (5' Guanylic Acid)IBA
01/2019
1InterferonsIBA
01/2019
1ChemokinesIBA
01/2019
1Biomarkers (Surrogate Marker)IBA
01/2018
1AZD1390IBA
01/2018
1Carrier Proteins (Binding Protein)IBA
10/2017
1SyndecansIBA
10/2017
1Peptides (Polypeptides)IBA
05/2015
1ProdrugsIBA
01/2015
1PAMAM StarburstIBA
01/2015
1Poly(amidoamine)IBA
01/2015
1Aspartic Acid (Aspartate)FDA Link
10/2013
1Serine (L-Serine)FDA Link
10/2013
1Alanine (L-Alanine)FDA Link
10/2013
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
10/2013
1D-luciferinIBA
01/2013
1Oxygen (Dioxygen)IBA
12/2012
1Cysteine (L-Cysteine)FDA Link
12/2012
1Doxorubicin (Adriamycin)FDA LinkGeneric
12/2012
1Glutathione (Reduced Glutathione)IBA
12/2012
1PolymersIBA
11/2012
1Temozolomide (Temodar)FDA LinkGeneric
03/2012
1Bisbenzimidazole (Hoechst 33258)IBA
02/2011
1Photosensitizing Agents (Photosensitizers)IBA
02/2011
1Bromodeoxyuridine (BrdU)IBA
02/2011
1Insulin (Novolin)FDA Link
10/2009
12- morpholin- 4- yl- 6- thianthren- 1- yl- pyran- 4- oneIBA
10/2009
1CalicheamicinsIBA
08/2009
1Small Interfering RNA (siRNA)IBA
08/2009
1tyrosyl-DNA phosphodiesteraseIBA
05/2009
1Peptide Hydrolases (Proteases)FDA Link
01/2008
1Antimicrobial PeptidesIBA
01/2008
1Mitogen-Activated Protein Kinase 3IBA
03/2007
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2007
1Lovastatin (Mevacor)FDA LinkGeneric
01/2007
1Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
01/2007
1Amino AcidsFDA Link
08/2006
1Endoplasmic Reticulum Chaperone BiPIBA
08/2006
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
07/2006

Therapy/Procedure

12Therapeutics
01/2020 - 02/2003
5Radiotherapy
01/2018 - 01/2014
3Drug Therapy (Chemotherapy)
01/2018 - 12/2012
2Immunotherapy
01/2019 - 10/2005
1Precision Medicine
12/2020
1Intraperitoneal Injections
01/2013
1Injections
05/2008